Longevity Research

Resveratrol suppresses inflammation and free radicals: Study
Resveratrol, a popular plant extract shown to prolong life in yeast and lower animals due to its anti-inflammatory and antioxidant properties, appears also to suppress inflammation in humans, based on results from the first prospective human trial of the extract conducted by University at Buffalo endocrinologists.

Study suggests lincRNAs plays critical role in cell development, regulation
The recent discovery of more than a thousand genes known as large intergenic non-coding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough is now made even more compelling with the finding that dozens of these lincRNAs are induced by p53 (the most commonly mutated gene in cancer), suggesting that this class of ...

Merck signs non-exclusive license agreement with LabCorp for commercialization of genetic test
Merck today announced a non-exclusive license agreement with Laboratory Corporation of America Holdings for the commercialization of a genetic test that may help predict the response of patients with Hepatitis C virus infection to peginterferon alpha-based therapy.

Harold Varmus Returns To Politics
The Nobel Prize winner and former NIH director has received another presidential appointment: director of the National Cancer Institute. Ira Flatow and Varmus discuss the intersection of politics and science, the genetics of cancer and the process by which basic research becomes medicine.

Tech Alliance showcases early stage ventures
Five startups are presenting today at the state Technology Alliance's Innovation Showcase, an event intended to connect more early stage companies with investors.

Eban-based HIV/STD risk-reduction intervention improves safe-sex habits among high-risk African-American couples
A new study has found that heterosexual African American couples in which only one partner is HIV-positive practiced safer sexual behaviors after participating in a culturally specific intervention program designed to reduce the risk of HIV and other sexually transmitted diseases.

team takes high resolution photo of a K+ channel
Using chemical labeling and mass spectrometry-based techniques, Mark Chance, PhD, director of the Case Western Reserve University School of Medicine Center for Proteomics and Bioinformatics and professor of physiology and biophysics; Sayan Gupta, PhD, instructor at the Case Center for Proteomics and Bioinformatics; and a research team from the University of Oxford, for the first time, were able ...

Exceptional Longevity in Humans Accurately Predicted from Genetic Signatures
July 8, 2010 - While environment and family history are factors in healthy aging, genetic variants play a critical and complex role in conferring exceptional longevity, according to a new landmark study by a team of researchers from the Boston University Schools of Public Health and Medicine and the Boston Medical Center.

Uncertainty and Response
Critics of the recent Science paper on longevity study say that "several things stand out as unusual from this paper," as Daniel MacArthur put it at his blog , Genetic Future.

Human Genome Project will live up to its potential: NIH director
A decade after the historic completion of the "book of life" -- the first blueprint of human DNA, the benefits of the Human Genome Project still lie ahead. However, Francis Collins, director of the U.S. National Institute of Health (NIH), is "confident" the project will live up to its potential.